Antibiotics without insurance cost in 2026
Antibiotics without insurance costs $3 to $78 per prescription in 2026, and most people pay about $15.
What moves the price
- The drug matters a lot, since amoxicillin is cheaper than azithromycin.
- The pharmacy chosen changes the price, even in the same town.
- A coupon or discount card can cut the cash price by a large amount.
- The number of pills and the strength change the total.
- Brand name drugs cost more than generics.
- Where you live. Prices in big cities usually run higher than in small towns.
What is included
The price is for the pills or liquid only. A doctor visit or telehealth visit to get the prescription is a separate cost. Some pharmacies add small fees, and prices change often. Prices are for information only. Confirm costs and care with a licensed provider.
Antibiotic cash prices by drug
| Drug and amount | Retail price | With discount coupon |
|---|---|---|
| Amoxicillin, 30 capsules, 250 mg | $14.18 | $4.20 |
| Amoxicillin, 30 capsules, 500 mg | $15.05 | $10.50 |
| Amoxicillin, 21 capsules, 500 mg | $18.96 | $3.22 to $15.73 |
| Azithromycin generic, 6 tablets, 250 mg | $23.54 to $37.49 | $9.38 to $18.36 |
| Azithromycin, 6 tablets, 250 mg (SingleCare) | $78 | $6 |
Average prices in US dollars. Source: GoodRx.
Ways to pay less
- Use a free pharmacy discount coupon, which can bring amoxicillin down to about $3 to $12.
- Compare prices at a few pharmacies, because Walmart and Kroger often list the lowest cash prices.
- Ask for the generic version instead of the brand name.
What price guides say
We checked 5 price guides and read every number on their pages. They do not all measure the same thing, so the ranges on this page come from putting them side by side.
- GoodRx: Azithromycin cost without insurance
- GoodRx: Amoxicillin cost without insurance
- SingleCare: Azithromycin without insurance
- SingleCare: Amoxicillin prices and coupons
- Drugs.com: Amoxicillin price guide
Common questions
How much does this cost in 2026?
Antibiotics without insurance costs $3 to $78 per prescription in 2026, and most people pay about $15. Most people pay about $15 per prescription. The low end is $3 and the high end is $78.
What changes the price the most?
The biggest factors are: The drug matters a lot, since amoxicillin is cheaper than azithromycin; The pharmacy chosen changes the price, even in the same town; A coupon or discount card can cut the cash price by a large amount.
How can I pay less?
Use a free pharmacy discount coupon, which can bring amoxicillin down to about $3 to $12. Compare prices at a few pharmacies, because Walmart and Kroger often list the lowest cash prices. Ask for the generic version instead of the brand name.
Where do these numbers come from?
From 5 named price guides: GoodRx, GoodRx, SingleCare, SingleCare, Drugs.com. Each one is linked on this page with the date we read it.
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