Entresto costs $295 to $900 a month in 2026
Brand name Entresto costs $600 to $900 a month for 60 tablets without insurance in 2026, with Drugs.com putting the cash price at about $734. Entresto was one of the first ten drugs picked for Medicare price negotiation, and the negotiated price of $295 a month took effect January 1, 2026, down 53 percent from the old list price of about $628. Most Medicare Part D patients pay about $25 to $50 a month after that, and Extra Help patients pay $0 to $10. Generic sacubitril valsartan is now on the market and brings the cash price under $100 at many pharmacies with a coupon.
What price guides say
We checked 4 price guides and read every number on their pages on October 7, 2026. They do not all measure the same thing, so read each line for what it counts.
| Source | What it found |
|---|---|
| Drugs.com | Drugs.com lists the brand cash price at $600 to $900 a month, and says many Medicare Part D patients pay about $25 to $50 a month. |
| CoveredUSA | CoveredUSA lists the brand cash price at $600 to $700 a month, a Medicare maximum of $295 a month, and generic at $45 to $255 with discount cards. |
| SingleCare | SingleCare lists a $295 out of pocket cost for Medicare in 2026, which averages about $25 a month, and a generic coupon price of $48 for 30 days. |
| The Derm Digest | The Derm Digest lists the negotiated Entresto price at $295 for a 30 day supply, down from a 2023 list price of $628. |
What pushes the price up
| What | Why it matters |
|---|---|
| Brand or generic | Generic sacubitril valsartan is the same drug and costs a fraction of the brand. Ask for it. |
| Medicare | $295 is the maximum Medicare pays for the brand. Your plan copay is usually $25 to $50 and the 2026 Part D cap is $2,100 a year. |
| Commercial insurance | Most plans cover Entresto for heart failure at a tier 2 or 3 copay. The Novartis copay card can take it to $10. |
| The dose | 24/26 mg, 49/51 mg and 97/103 mg tablets cost about the same per month. |
| The pharmacy | Cash prices for the brand swing $300 between stores. |
What the price includes
The price covers 60 tablets, one twice a day. Blood pressure and kidney checks every few months are separate. It does not include tax or extras the provider adds on the day.
Does insurance cover it
Most Medicare Part D and commercial plans cover Entresto for heart failure. Drugs.com says many Part D patients pay about $25 to $50 a month, and people with Extra Help may pay $0 to about $10. Medicare's negotiated price started January 1, 2026. Commercial plans often place it on a middle tier with a copay. The Novartis copay card can lower that copay for eligible people. Plans differ, so check your drug list. Ask if the generic is covered, since it may cost less.
How to judge your quote
- Ask your doctor if the generic sacubitril valsartan is right for you.
- Ask the pharmacist for the cash price of the brand and of the generic.
- Check that your Medicare Part D plan lists Entresto or the generic.
- With commercial insurance, ask about the Novartis copay card.
- Compare the total with the range above: $295 to $900 per month for most people in 2026.
Ways to pay less
- Ask your doctor to write for generic sacubitril valsartan. That one change can cut the bill by hundreds a month.
- On Medicare, check that your Part D plan lists Entresto or the generic for 2026 during open enrollment.
- Use the Novartis copay card with commercial insurance. Most patients pay $10 or less.
- If uninsured, apply to Novartis Patient Assistance for free brand Entresto, or price the generic with GoodRx.
How we got these numbers
The range on this page comes from Drugs.com, CoveredUSA, SingleCare and The Derm Digest. We opened each source page and read every number on it on October 7, 2026. Where the sources disagree, the table above shows each one so you can see the spread. These are planning ranges, not quotes. The written price you are given is the real price.
Common questions
How much does Entresto cost without insurance?
Drugs.com lists $600 to $900 a month. CoveredUSA lists $600 to $700.
How much does Entresto cost on Medicare?
Drugs.com says many Part D patients pay about $25 to $50 a month. The negotiated price is $295 a month, per The Derm Digest.
Is there a generic?
Yes. CoveredUSA lists generic sacubitril valsartan at $45 to $255 with discount cards. SingleCare lists a $48 coupon price for 30 days.
Can I get copay help?
Drugs.com says the Novartis card can bring a commercial copay to no more than $10.