Xiidra cost in 2026
Xiidra costs about $729 to $787 per box of 60 vials without insurance in 2026, at retail cash prices.
What moves the price
- The pack and strength. Prices here are for Box of 60 single-use containers of 5% eye drops.
- Your coverage. Commercial insurance, Medicare and cash pay all get very different prices.
- The pharmacy. Cash prices for the same pack can differ by hundreds of dollars between stores.
- Whether a generic or biosimilar is on sale. No generic available; brand only.
What is included
The prices on this page are what a pharmacy charges for Box of 60 single-use containers of 5% eye drops, before any insurance. Your own cost depends on your plan, your deductible and any savings card. Ask your pharmacist for the cash price and your insured price, and pay the lower one.
Ways to pay for Xiidra
| How you pay | What it costs |
|---|---|
| Cash price without insurance | $729 to $787 per box of 60 vials (SingleCare) |
| With the maker's savings card | Xiidra copay card (listed on Drugs.com): commercially insured and eligible may pay $0 per 30-day prescription, with a maximum monthly benefit. Uninsured fixed cash price: $225 for 30 days, $450 for 60 days, $675 for 90 days. Phone 877-494-4372. |
| Medicare | Xiidra is not on the Medicare negotiation lists for 2026, 2027 or 2028. |
| Free drug program | Bausch + Lomb Patient Assistance Program: for people with no prescription coverage for the drug, income based on the federal poverty level, an FDA-approved diagnosis, and US citizenship or legal residency. A bridge program may help with a coverage gap. Phone 855-770-0424. |
| Generic or biosimilar | No generic available; brand only. |
Average prices in US dollars. Source: Drugs.com.
Ways to pay less
- Xiidra copay card (listed on Drugs.com): commercially insured and eligible may pay $0 per 30-day prescription, with a maximum monthly benefit. Uninsured fixed cash price: $225 for 30 days, $450 for 60 days, $675 for 90 days. Phone 877-494-4372.
- Bausch + Lomb Patient Assistance Program: for people with no prescription coverage for the drug, income based on the federal poverty level, an FDA-approved diagnosis, and US citizenship or legal residency. A bridge program may help with a coverage gap. Phone 855-770-0424.
- Compare cash prices at several pharmacies with a free discount card before you pay.
- Ask your doctor if a generic or a lower cost drug would work for you.
What price guides say
We checked 5 price guides and read every number on their pages. They do not all measure the same thing, so the ranges on this page come from putting them side by side.
- Drugs.com: Xiidra Prices, Coupons, Copay Cards & Patient Assistance
- SingleCare: Xiidra Coupons & Prices
- Drugs.com: Xiidra Eye Drops
- CMS: Selected Drugs and Negotiated Prices
- CMS: Fact sheet: Medicare negotiation selected drug list, IPAY 2028
Common questions
How much does this cost in 2026?
Xiidra costs about $729 to $787 per box of 60 vials without insurance in 2026, at retail cash prices. Most people pay about $758 per box of 60 vials. The low end is $729 and the high end is $787.
What changes the price the most?
The biggest factors are: The pack and strength. Prices here are for Box of 60 single-use containers of 5% eye drops; Your coverage. Commercial insurance, Medicare and cash pay all get very different prices; The pharmacy. Cash prices for the same pack can differ by hundreds of dollars between stores.
How can I pay less?
Xiidra copay card (listed on Drugs.com): commercially insured and eligible may pay $0 per 30-day prescription, with a maximum monthly benefit. Uninsured fixed cash price: $225 for 30 days, $450 for 60 days, $675 for 90 days. Phone 877-494-4372. Bausch + Lomb Patient Assistance Program: for people with no prescription coverage for the drug, income based on the federal poverty level, an FDA-approved diagnosis, and US citizenship or legal residency. A bridge program may help with a coverage gap. Phone 855-770-0424. Compare cash prices at several pharmacies with a free discount card before you pay.
Where do these numbers come from?
From 5 named price guides: Drugs.com, SingleCare, Drugs.com, CMS, CMS. Each one is linked on this page with the date we read it.
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