Dupixent costs $3,993 to $5,449 a month in 2026
Dupixent costs $4,193 per carton at Regeneron and Sanofi's list price as of January 2026. One carton is two prefilled pens, usually a month's supply. Without insurance the cash price at a specialty pharmacy runs $3,993 to $5,449 a month, and some retail listings top $5,500. Almost nobody pays that. About 68 percent of commercially insured patients pay $0 to $100 a month with the Dupixent MyWay copay card, and about 79 percent of Medicare Part D patients pay $0 to $100 under the 2026 cap. There is no generic or biosimilar. CoveredUSA lists $4,193 per carton as of January 2026, cash prices of $3,993 to $5,449 a month, and a Medicare Part D cap of $2,100.
What price guides say
We checked 3 price guides and read every number on their pages on October 7, 2026. They do not all measure the same thing, so read each line for what it counts.
| Source | What it found |
|---|---|
| CoveredUSA | CoveredUSA lists $4,193 per carton as of January 2026, cash prices of $3,993 to $5,449 a month, and a Medicare Part D cap of $2,100. |
| MedFinder | MedFinder lists about $4,193 a month, a discount card price of about $4,026, and 68% of patients paying $0 to $100 with the copay card. |
| SingleCare | SingleCare says a month without insurance can cost about $5,377, or about $3,787 with a SingleCare card. |
What pushes the price up
| What | Why it matters |
|---|---|
| Insurance | Commercial plans cover Dupixent for asthma, eczema, COPD and nasal polyps with prior authorization. The copay card takes most patients to $0 to $100. |
| Medicare | The 2026 Part D out of pocket cap is $2,100 a year, so most patients hit it in the first month or two. |
| The dose | 300 mg every 2 weeks is the common adult dose. 200 mg and every 4 week schedules change the monthly bill. |
| Discount cards | SingleCare and similar cards bring the cash price to about $3,785 to $4,026 a month. |
| Patient assistance | Dupixent MyWay gives the drug free to uninsured patients who meet income limits. |
What the price includes
The price covers the two pens in a carton. Nurse training, the first injection visit and follow up appointments are billed separately. It does not include tax or extras the provider adds on the day.
Does insurance cover it
Many commercial plans cover Dupixent, often after prior approval. With commercial insurance, the MyWay copay card can cut your cost. CoveredUSA says it can cover up to $13,000 a year. MedFinder says about 68% of commercial patients pay $0 to $100 a month. On Medicare Part D, the 2026 yearly out of pocket cap is $2,100. If you have no insurance, MyWay may give it free if you meet the income and residency rules. Ask your doctor's office to help with the forms.
How to judge your quote
- Ask the pharmacy for the cash price of two pens.
- Ask if your plan needs prior approval for your condition.
- Ask about the Dupixent MyWay copay card before your first fill.
- A fair price for an insured patient is far below the list price.
- Compare the total with the range above: $3,993 to $5,449 per month for most people in 2026.
Ways to pay less
- Enroll in Dupixent MyWay before your first fill. It handles the copay card, prior authorization appeals and free drug for the uninsured.
- If your plan denies it, ask your doctor to file an appeal with photos and a step therapy history. Most denials are overturned.
- On Medicare, ask about Extra Help if your income is low. It cuts the monthly cost to under $13.
- Never pay the $5,000 cash price. Call the manufacturer line first.
How we got these numbers
The range on this page comes from CoveredUSA, MedFinder and SingleCare. We opened each source page and read every number on it on October 7, 2026. Where the sources disagree, the table above shows each one so you can see the spread. These are planning ranges, not quotes. The written price you are given is the real price.
Common questions
How much does Dupixent cost a month?
CoveredUSA lists $4,193 per carton as of January 2026. Cash prices at specialty pharmacies run $3,993 to $5,449.
How much does Dupixent cost with insurance?
MedFinder says about 68% of patients pay $0 to $100 a month with the MyWay copay card.
How much does it cost on Medicare?
CoveredUSA lists a 2026 yearly out of pocket cap of $2,100. MedFinder says about 79% of Part D patients pay $0 to $100.
Is there a cheaper way to buy it?
SingleCare says a discount card can bring it to about $3,787 a month. Uninsured patients may get it free through MyWay if they meet the income rules.