Prolia cost in 2026
Prolia costs about $1,876 to $2,460 per shot without insurance in 2026, at retail cash prices.
What moves the price
- The pack and strength. Prices here are for 1 prefilled syringe of 60 mg per 1 mL, given once every 6 months.
- Your coverage. Commercial insurance, Medicare and cash pay all get very different prices.
- The pharmacy. Cash prices for the same pack can differ by hundreds of dollars between stores.
- Whether a generic or biosimilar is on sale. Yes, biosimilars are available: Sandoz's Jubbonti (denosumab bbdz) launched June 2 2025. Others were approved in 2025 (Ospomyv, Stoboclo, Conexxence).
What is included
The prices on this page are what a pharmacy charges for 1 prefilled syringe of 60 mg per 1 mL, given once every 6 months, before any insurance. Your own cost depends on your plan, your deductible and any savings card. Ask your pharmacist for the cash price and your insured price, and pay the lower one.
Ways to pay for Prolia
| How you pay | What it costs |
|---|---|
| Maker list price | $1,875 per shot |
| Cash price without insurance | $1,876 to $2,460 per shot (GoodRx) |
| With the maker's savings card | Amgen SupportPlus Co-Pay Program: for people with commercial insurance (employer or self bought). You may pay as little as $0 per dose, subject to program maximums. |
| Medicare | Not on the Medicare negotiation list (not on the 2026, 2027 or 2028 lists). |
| Free drug program | Amgen Safety Net Foundation (may give Prolia free to people who are uninsured or not covered and have income under its limit). |
| Generic or biosimilar | Yes, biosimilars are available: Sandoz's Jubbonti (denosumab bbdz) launched June 2 2025. Others were approved in 2025 (Ospomyv, Stoboclo, Conexxence). |
Average prices in US dollars. Source: AIS Health (MMIT).
Ways to pay less
- Amgen SupportPlus Co-Pay Program: for people with commercial insurance (employer or self bought). You may pay as little as $0 per dose, subject to program maximums.
- Amgen Safety Net Foundation (may give Prolia free to people who are uninsured or not covered and have income under its limit).
- Compare cash prices at several pharmacies with a free discount card before you pay.
- Ask your doctor if a generic or a lower cost drug would work for you.
What price guides say
We checked 6 price guides and read every number on their pages. They do not all measure the same thing, so the ranges on this page come from putting them side by side.
- AIS Health (MMIT): Sandoz Launches First Interchangeable Denosumab Biosimilars at Discounted WACs
- GoodRx: Prolia prices
- SingleCare: Prolia Coupons & Prices
- Drugs.com: Prolia price guide
- Prolia.com: Paying for Prolia
- CareRoute: Prolia injection cost in 2026
Common questions
How much does this cost in 2026?
Prolia costs about $1,876 to $2,460 per shot without insurance in 2026, at retail cash prices. Most people pay about $2,168 per shot. The low end is $1,876 and the high end is $2,460.
What changes the price the most?
The biggest factors are: The pack and strength. Prices here are for 1 prefilled syringe of 60 mg per 1 mL, given once every 6 months; Your coverage. Commercial insurance, Medicare and cash pay all get very different prices; The pharmacy. Cash prices for the same pack can differ by hundreds of dollars between stores.
How can I pay less?
Amgen SupportPlus Co-Pay Program: for people with commercial insurance (employer or self bought). You may pay as little as $0 per dose, subject to program maximums. Amgen Safety Net Foundation (may give Prolia free to people who are uninsured or not covered and have income under its limit). Compare cash prices at several pharmacies with a free discount card before you pay.
Where do these numbers come from?
From 6 named price guides: AIS Health (MMIT), GoodRx, SingleCare, Drugs.com, Prolia.com, CareRoute. Each one is linked on this page with the date we read it.
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