Xifaxan cost in 2026
Xifaxan costs about $2,865 to $3,435 per month without insurance in 2026, at retail cash prices.
What moves the price
- The pack and strength. Prices here are for 60 tablets of 550 mg (550 mg twice a day, about 30 days).
- Your coverage. Commercial insurance, Medicare and cash pay all get very different prices.
- The pharmacy. Cash prices for the same pack can differ by hundreds of dollars between stores.
- Whether a generic or biosimilar is on sale. No generic is on sale in the US now. Drugs.com says a generic has been approved by the FDA but it is not commercially available, and GoodRx lists no lower cost generic.
What is included
The prices on this page are what a pharmacy charges for 60 tablets of 550 mg (550 mg twice a day, about 30 days), before any insurance. Your own cost depends on your plan, your deductible and any savings card. Ask your pharmacist for the cash price and your insured price, and pay the lower one.
Ways to pay for Xifaxan
| How you pay | What it costs |
|---|---|
| Maker list price | $2,696 per month |
| Cash price without insurance | $2,865 to $3,435 per month (GoodRx) |
| With the maker's savings card | Commercially insured patients (not on Medicare, Medicaid, VA, DOD or TRICARE) can use the Xifaxan savings card; the maker says 87% of eligible patients paid $10 or less. Cash payers do not qualify. |
| Medicare | Medicare negotiated price of $1,000 for a 30 day supply from Jan 1 2027. |
| Free drug program | Bausch Health Patient Assistance Program: for US residents who are uninsured, underinsured, or on Medicare or Medicaid, with household income up to 300% of the federal poverty level (1-833-862-8727). |
| Generic or biosimilar | No generic is on sale in the US now. Drugs.com says a generic has been approved by the FDA but it is not commercially available, and GoodRx lists no lower cost generic. |
Average prices in US dollars. Source: Drugs.com.
Ways to pay less
- Commercially insured patients (not on Medicare, Medicaid, VA, DOD or TRICARE) can use the Xifaxan savings card; the maker says 87% of eligible patients paid $10 or less. Cash payers do not qualify.
- Bausch Health Patient Assistance Program: for US residents who are uninsured, underinsured, or on Medicare or Medicaid, with household income up to 300% of the federal poverty level (1-833-862-8727).
- Compare cash prices at several pharmacies with a free discount card before you pay.
- Ask your doctor if a generic or a lower cost drug would work for you.
What price guides say
We checked 6 price guides and read every number on their pages. They do not all measure the same thing, so the ranges on this page come from putting them side by side.
- Drugs.com: Xifaxan Prices, Coupons, Copay Cards & Patient Assistance
- GoodRx: Xifaxan
- GoodRx: What is Xifaxan
- SingleCare: Xifaxan Coupons & Prices
- Xifaxan.com: Access & Savings
- PrescriberPoint: Bausch Health Patient Assistance Program
Common questions
How much does this cost in 2026?
Xifaxan costs about $2,865 to $3,435 per month without insurance in 2026, at retail cash prices. Most people pay about $3,150 per month. The low end is $2,865 and the high end is $3,435.
What changes the price the most?
The biggest factors are: The pack and strength. Prices here are for 60 tablets of 550 mg (550 mg twice a day, about 30 days); Your coverage. Commercial insurance, Medicare and cash pay all get very different prices; The pharmacy. Cash prices for the same pack can differ by hundreds of dollars between stores.
How can I pay less?
Commercially insured patients (not on Medicare, Medicaid, VA, DOD or TRICARE) can use the Xifaxan savings card; the maker says 87% of eligible patients paid $10 or less. Cash payers do not qualify. Bausch Health Patient Assistance Program: for US residents who are uninsured, underinsured, or on Medicare or Medicaid, with household income up to 300% of the federal poverty level (1-833-862-8727). Compare cash prices at several pharmacies with a free discount card before you pay.
Where do these numbers come from?
From 6 named price guides: Drugs.com, GoodRx, GoodRx, SingleCare, Xifaxan.com, PrescriberPoint. Each one is linked on this page with the date we read it.
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