Trintellix costs $299 to $714 a month without insurance in 2026
Trintellix costs about $299 to $714 a month without insurance in 2026. The price depends on the pharmacy, the dose and whether you use a coupon. GoodRx lists a coupon price as low as $299.10 for 30 tablets, against an average retail price of $650.96. SingleCare lists its coupon prices from $491.07 to $558.66 for 30 tablets of 20 mg. There is no generic yet, so the brand price is the only choice. Shop around before you fill it.
What price guides say
We checked 3 price guides and read every number on their pages on October 7, 2026. They do not all measure the same thing, so read each line for what it counts.
| Source | What it found |
|---|---|
| GoodRx | GoodRx lists Trintellix for as low as $299.10 with a coupon, against an average retail price of $650.96, and a savings card that can bring it to $10 per fill. |
| Drugs.com | Drugs.com lists 30 tablets at $465.93 to $576.00 depending on the pharmacy, and says the maker's savings card can bring a fill to $10 for insured patients. |
| SingleCare | SingleCare lists an average retail price of $714.03 for 30 tablets of 20 mg and coupon prices from $491.07 to $558.66. |
Trintellix price by way to pay (30 tablets)
| Way to pay | Price | Source |
|---|---|---|
| Average retail price | $650.96 | GoodRx |
| Average retail price, 20 mg | $714.03 | SingleCare |
| GoodRx coupon, lowest | $299.10 | GoodRx |
| SingleCare coupon | $491.07 to $558.66 | SingleCare |
| Blink Health, 20 mg | $517.58 | Drugs.com |
| HealthWarehouse mail order | $576.00 | Drugs.com |
| Maker savings card (commercial insurance) | $10 per fill | Drugs.com |
Every number in this table was read on one of the source pages listed at the bottom of this page.
What pushes the price up
| What | Why it matters |
|---|---|
| Pharmacy | The same 30 tablets can cost $491.07 at Kroger or $558.66 at Food Lion with a SingleCare coupon, so the store you pick matters. |
| Coupon or card | GoodRx, SingleCare and other cards cut the retail price a lot. Without one, you may pay the full $650.96 average retail price. |
| Dose | Retail prices for 5 mg, 10 mg and 20 mg are close, but coupon prices differ by dose and store, so check your exact dose. |
| Quantity | Prices are for 30 tablets. A 90 day fill may bring a lower price per tablet at some pharmacies, so ask for both prices. |
| Insurance | With commercial insurance, the maker's savings card can bring your cost to $10 a fill. Without it, you pay cash. |
What the price includes
The price is for a pill bottle of Trintellix, usually 30 tablets, filled at a pharmacy. It does not include the doctor visit, lab tests or any other medicine. Some coupons add a small sign up bonus, such as $3 at SingleCare. Mail order pharmacies may add shipping. Generic versions are not sold yet. It does not include tax or extras the provider adds on the day.
Does insurance cover it
Many insurance plans cover Trintellix, but it is a brand drug with no generic. That often puts it in a higher cost tier, so your copay may be high, and some plans ask for prior approval. If your plan does cover it and you have commercial insurance, the maker's savings card can lower your cost to $10 per fill. The card has limits and does not work with government plans. If your plan says no, ask your doctor to file an appeal. If you are uninsured, compare coupon prices, since they can be far below the retail price.
When a doctor orders it
Trintellix is a prescription medicine. A doctor orders it after talking with you about your symptoms and health history. It is not sold over the counter. Your doctor may ask you to try other medicines first, or may pick it if other medicines did not work or caused side effects. Do not start or stop it on your own. If cost is a worry, tell your doctor, since there may be other choices.
How to judge your quote
- Ask the pharmacy for the cash price and the coupon price for 30 tablets.
- Check the price at two or three stores, since the same fill varied by over $60 in one source.
- Make sure the quote is for your dose and the same number of tablets.
- If you have commercial insurance, ask if the savings card can lower your copay.
- Compare the total with the range above: $299 to $714 per month for most people in 2026.
Ways to pay less
- Compare coupon prices at GoodRx, SingleCare and Drugs.com before you fill. The same pill ranged from $299.10 to over $550 across these sources.
- If you have commercial insurance, ask for the Trintellix savings card. It can bring your cost to $10 per fill, with up to $100 off each 30 day fill.
- Ask your doctor if a 90 day fill is right for you. Some pharmacies charge less per tablet for a larger fill.
- Check mail order options such as HealthWarehouse, which listed $576 to $597.90 for 30 tablets, and compare them with local coupon prices.
- Ask your doctor about older generic medicines for your condition. Trintellix has no generic, so a generic option may cost far less.
How we got these numbers
The range on this page comes from GoodRx, Drugs.com and SingleCare. We opened each source page and read every number on it on October 7, 2026. Where the sources disagree, the table above shows each one so you can see the spread. These are planning ranges, not quotes. The written price you are given is the real price.
Common questions
How much does Trintellix cost without insurance?
Most cash prices fall between $299 and $714 for 30 tablets. GoodRx lists a coupon price as low as $299.10. The average retail price is $650.96 at GoodRx and $714.03 for 20 mg at SingleCare.
Is there a generic for Trintellix?
No. Drugs.com says Trintellix is sold as a brand name only and that generic versions are not yet available. That keeps the price high compared with older medicines.
Is there a savings card for Trintellix?
Yes, for people with commercial insurance. Drugs.com says eligible patients may pay $10 per 30 or 90 day prescription, with savings up to $100 per 30 day fill. It does not work for cash buyers.
Which pharmacy has the lowest price?
It changes by day and place. SingleCare lists Kroger and Harris Teeter at $491.07 for 20 mg, and GoodRx lists a low of $299.10. Check each app for your zip code.
Can I use a coupon and insurance together?
Usually you pick one for each fill. A discount card price is a cash price, so it may not count toward your deductible. Ask the pharmacist to run both and compare.